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优利科(上海)生命科学有限公司
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Anti-IGSF3
IGSF3抗体
详询
兔
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KLH conjugated synthetic peptide derived from human IGSF3
IgG
Lyophilized or Liquid
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200
-20℃
1mg/ml
详询
英文名称 Anti-IGSF3 |
中文名称 免疫球蛋白超家族成员3抗体 |
别 名 EWI 3; EWI3; Glu Trp Ile EWI motif containing protein 3; Immunoglobin superfamily member 3; Immunoglobulin superfamily member 3; KIAA0466; MGC117164; V8 antibody; IGSF3_HUMAN. |
浓 度 1mg/1ml |
规 格 0.2ml/200μg |
抗体来源 Rabbit |
克隆类型 polyclonal |
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit |
产品类型 一抗 |
研究领域 细胞生物 细胞粘附分子 细胞表面分子 |
蛋白分子量 predicted molecular weight: 133kDa |
性 状 Lyophilized or Liquid |
免 疫 原 KLH conjugated synthetic peptide derived from human IGSF3 |
亚 型 IgG |
纯化方法 affinity purified by Protein A |
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200 |
(石蜡切片需做抗原修复) |
not yet tested in other applications. |
optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule. |
Subcellular Location : Membrane; Single-pass type I membrane protein |
Tissue Specificity : It is expressed in a wide range of tissues with high expression in placenta, kidney and lung. |
Similarity : Contains 8 Ig-like C2-type (immunoglobulin-like) domains. |
Database links : UniProtKB/Swiss-Prot: O75054.3 |
IL-6(Interleukin-6) 白介素6(白细胞介素-6)(多肽抗原) |
IL-10(Interleukin-10) 白介素10(白细胞介素-10)(抗原) |
IL-10(Interleukin-10) 白介素10(白细胞介素-10)(抗原) |
IL-8 白介素8(白细胞介素-8)(抗原) |
Insulin Receptor(ISR) 胰岛素受体(抗原) |
ITG-α(Integrin α chain) 整合素-α(抗原) |
LDL-R(Low-density lipoprotein receptor precursor) 低密度脂蛋白受体(抗原) |
Ki-67 Antigen Ki-67 Antigen(抗原) |
Kiss-1(Metastasis-suppressor KiSS-1 precursor) 肿瘤转移抑制基因(抗原) |
重组K3蛋白 |
Leptin 瘦素(抗原) |
Lpin1 protein Lpin1 protein(抗原) |
Lumbrokinase 蚯蚓纤溶酶(蚓激酶抗原) |
Livin (Inhibitors of apoptosis proterins Livin) 一种新的凋亡抑制蛋白(抗原) |
p38 MAPK 丝裂原活化蛋白激酶p38(抗原) |
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