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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
63
- 靶点:
/
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-Integrin alpha L/CD11a
- 抗体名:
Integrin alpha L/CD11a抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
见产品详情
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
见产品详情
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-Integrin alpha L/CD11a |
| 中文名称 整合素αL抗体Integrin αL |
| 别 名 Integrin alpha-L; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; Lymphocyte antigen 15; Ly-15; CD11 antigen-like family member A; CD_antigen; CD11a; ITAL_HUMAN. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep |
| 产品类型 一抗 |
研究领域 细胞生物 干细胞 细胞粘附分子 ![]() |
| 蛋白分子量 predicted molecular weight: 126kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human Integrin alpha L (292-339aa) |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3(intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. |
| Function : Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. |
| Subunit : Heterodimer of an alpha and a beta subunit. Alpha-L associates with beta-2. |
| Subcellular Location : Membrane; Single-pass type I membrane protein. |
| Tissue Specificity : Leukocytes. |
| Similarity : Belongs to the integrin alpha chain family. |
| Contains 7 FG-GAP repeats. |
| Contains 1 VWFA domain. |
Database links : UniProtKB/Swiss-Prot: P20701.3![]() |
| BrdU (Bromodeoxyuridine) 溴脱氧尿苷 |
| C5 过敏毒素C5(补体C5)抗原 |
| CA125 (Ovarian cancer antigen) 卵巢癌抗原(抗原) |
| CAD(Caspase-Activated Deoxyribonuclease) Caspase 激活的脱氧核糖核酸酶(抗原) |
| Calponin 1 钙调节蛋白-1(抗原) |
| Caspase-1 (ICE; CASP-1;P45) 天冬氨酸-胱氨酸特异性蛋白酶家族(抗原) |
| Caspase-3 (CPP32) 半胱胺酸蛋白酶蛋白-3(抗原) |
| Caspase-6 (NT) 半胱胺酸蛋白酶蛋白-6(抗原) |
| Caspase-6 (CT) 半胱胺酸蛋白酶蛋白-6(抗原) |
| Caspase-9 白介素1-β转化酶样凋亡蛋白酶6(抗原) |
| Caspase-9 白介素1-β转化酶样凋亡蛋白酶6(抗原) |
| Caspase-10 半胱胺酸蛋白酶-10(抗原) |
| Caspase-13 半胱胺酸蛋白酶蛋白-13(抗原) |
| CD19(B-lymphocyte antigen CD19 precursor) CD19(抗原) |
| CD31 (PECAM-1) 血小板内皮细胞黏附分子-1(抗原) |
| Immunoglobuin binding protein-1(CD79A)IGBP-1 免疫球蛋白结合蛋白-1 |
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