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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
/
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-IL-17
- 抗体名:
IL-17抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
见产品详情
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
见产品详情
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-IL-17 |
| 中文名称 白介素-17抗体 |
| 别 名 Interleukin-17; CTLA 8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL17A; IL-17A; Interleukin 17; Interleukin 17A; Interleukin17; Interleukin17A. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg 0.2ml/200μg 1ml/1mg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Mouse, Rat |
| 产品类型 一抗 |
研究领域 肿瘤 细胞生物 免疫学 转录调节因子 ![]() |
| 蛋白分子量 predicted molecular weight: 15kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from mouse IL-17 (85-150aa) |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts; the enhancement of surface expression of ICAM 1 in fibroblasts; activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17. |
| Function : Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. |
| Subunit : Homodimer. |
| Subcellular Location : Secreted. |
| Tissue Specificity : Restricted to a subset of activated T-cells. |
| Post-translational modifications : Found both in glycosylated and nonglycosylated forms. |
| Similarity : Belongs to the IL-17 family. |
| Database links : UniProtKB/Swiss-Prot: Q62386.1 mouse |
白细胞介素17(IL-17A)是一种来源于活化T淋巴细胞的细胞因子,具有较广泛的生物学活性,它能够通过诱导基质细胞产生前炎性细胞因子和造血细胞因子参与机体免疫调节及部分炎症反应,因此白细胞介素IL-17A可能是某些疾病发生发展的重要因素之一。Interleukin-17 原称CTLA-8, 是T细胞表达的多肽,参与造血干系统的调节,已经显示IL-17促进纤维母细胞产生IL-6,IL-8和G-CSF。![]() |
| Angiotensin II receptor(AngⅡ) 血管紧张素Ⅱ受体(抗原) |
| AhDMT 1 植物蛋白大豆、花生AhDMT-1(抗原) |
| Akt/PKC(Protein Kinase C,PKC) 蛋白激酶C(抗原) |
| ADM/AM Protein (Adrenomedullin) 肾上腺髓质素(1-52) |
| β1-adrenergic receptor 肾上-腺素能受体β1(抗原) |
| Annexin V 膜粘连蛋白-5(抗原) |
| AQP4(aquaporin Protein-4) 水通道蛋白-4(抗原) |
| B7-H4 B7-H4(抗原) |
| BADH2 (Betaine-aldehyde dehydrogenase ) BADH2抗原 |
| BGP(Bone Gla-protein) 骨钙素(抗原) |
| BK channel (stretch-activated Kca channel) BK通道蛋白(抗原) |
| BKCa channels(calcium-activated potassium channel) 钙激活钾通道蛋白 |
| BTG2/TIS21(B-cell translocation gene 2) BTG2(抗原) |
| C-fos(i mmediate early gene, ieg) 即刻早期基因(是一种原癌基因)抗原 |
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文献和实验上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 豚鼠白介素-17 (IL- 17 )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗豚鼠 IL-17 单抗包被于酶标板上,标准品和样品中的 IL-17与单抗结合,加入生物
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 小鼠白介素-17 (IL-17)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗小鼠 IL-17 单抗包被于酶标板上,标准品和样品中的 IL-17与单抗结合,加入生物素化的抗小鼠
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠白介素 -17(IL-17)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 IL-17 单抗包被于酶标板上,标准品和样品中的 IL-17 与单抗结合,加入生物素化的抗大鼠 IL-17 ,形成免疫复合物连接














