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- 英文名:
Human FGFb (诊断原料,肿瘤标志物)
Recombinant Human FGFb
Catalog #: DC046 Derived From: E.coli
Description:
Recombinant Human Fibroblast Growth Factor 2/FGF-2/FGFb (Gly132-Ser288) is produced by E.coli expression system and the target gene encoding Gly132-Ser288 is expressed.
Accession: P09038
Names(Known as):Fibroblast Growth Factor 2; FGF-2; Basic Fibroblast Growth Factor; bFGF; Heparin-Binding Growth Factor 2; HBGF-2; FGF2; FGFB
Quality Control:
Mol Mass: 17kDa AP Mol Mass: 16kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.
Shipping:
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Ion-exchange chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, aA02enal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
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文献和实验案例详情 患者男,65 岁,于 2020 年 11 月 22 日来我院体检。 心电图检查:1、窦性心律,2、正常心电图。实验室检查:肝功能及肾功能正常,血糖 6.23mmoL/L,甘油三酯 2.75mmoL/L,胆固醇及高密度脂蛋白胆固醇正常,乙肝五项都阴性,血常规及尿常规都正常。所查的两项肿瘤标志物中唯独甲胎蛋白异常升高。 按照常理,这么高的甲胎蛋白应差不多是肝癌了吧! 进一步诊查 然而,该体检者的肝脏超声结果却未发现有占位性病变。 1. 彩色多普勒超声 (泌尿系统、肝胆脾 + 双肾、甲状
酰胺酶(GLS)、尿苷磷酸化酶 1(UPase1)、组氨酸脱羧酶(HDC)、脂肪酸合成酶(FASN)和鸟氨酸脱羧酶(ODC),它们广泛参与食管癌相关的肿瘤代谢过程,其中 PYCR2 和 UPase1 被首次发现在食管癌中异常改变。研究结果表明脯氨酸生物合成,谷氨酸代谢,尿苷代谢,组氨酸代谢,脂肪酸合成,多胺生物合成等代谢通路在食管癌组织中发生了显著变化。这些癌症代谢相关信息有助于增加对癌症代谢重编程的理解。 基于 AFADESI-MSI 技术的空间分辨原位代谢组学方法,不仅可验证肿瘤原位标志物的可
。市面上可提供一些商品化的预先设计、优化的抗体组合试剂盒。这些试剂盒通过提供识别关键免疫和/或肿瘤细胞标志物的优化一抗组合,为新用户提供了构建多重荧光免疫组化抗体组合的简便途径。而开放渠道使研究人员能够灵活地添加他们自由选择的其他标志物。 b 选择抗体 与免疫学家和疾病专家合作,确定理想的一系列生物标志物可以回答手头的生物学问题。哪些标志物可以明确区分靶细胞表型与周围组织?是否有特定的标志物,其空间分布对于研究是否很重要?相关生物学问题是否涉及标志物的共定位和/或复杂细胞表型的相互
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