- 询价
- 近岸蛋白(Novoprotein)
- 中国
- DC235
- 2025年11月07日
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- 英文名：
Human LDH-A (诊断原料,肿瘤标志物）
Recombinant Human LDH-A
Catalog #: DC235 Derived From: E.coli
Description:
Recombinant Human L-Lactate Dehydrogenase A Chain/LDH-A/PIG19 (N-6His) is produced by E.coli expression system and the target gene encoding Met1-Phe332 is expressed with a 6His tag at the N-terminus.
Accession: P00338
Names(Known as):L-Lactate Dehydrogenase A Chain; LDH-A; Cell Proliferation-Inducing Gene 19 Protein; LDH Muscle Subunit; LDH-M; Renal Carcinoma Antigen NY-REN-59; LDHA
Quality Control:
Mol Mass: 38.8kDa AP Mol Mass: 37kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 50% Glycerol, pH 8.0.
Shipping:
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
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This chapter describes method for evaluation of nanomaterial cytotoxicity by examining effects on porcine kidney (LLC-PK1) and human cancerous liver cells (Hep G2). Several studies indicate that many nanoparticles are cleared from the body
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