- 询价
- 近岸蛋白(Novoprotein)
- 中国
- DC002
- 2025年11月07日
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- 文献和实验
- 技术资料
- 英文名：
Human G-CSF (诊断原料,肿瘤标志物）
Recombinant Human G-CSF
Catalog #: DC002 Derived From: E.coli
Description:
Recombinant Human Granulocyte Colony-Stimulating Factor/G-CSF is produced by E.coli expression system and the target gene encoding Thr31-Pro204 is expressed.
Accession: P09919-2
Names(Known as):Granulocyte Colony-Stimulating Factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim; CSF3; C17orf33; GCSF
Quality Control
Mol Mass: 18.8kDa AP Mol Mass: 16kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 0.004% Tween 80, 5% Mannitol, pH 4.0.
Shipping:
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Ion-exchange chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
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文献和实验Section.01 肺癌标志物 PD-L1 PD-L1——免疫检查点分子，属于 B7-CD28 免疫调节超家族。 定位：细胞膜。 功能：PD-L1 是一种跨膜蛋白。其主要生理功能是在免疫突触中与免疫 T 细胞表面的 PD-1 受体结合，传递抑制性信号，通过抑制 T 细胞活化和增殖来发挥作用。 肿瘤细胞或肿瘤微环境中的免疫细胞会高表达 PD-L1，与浸润 T 细胞的 PD-1 结合，从而“关停” T 细胞的杀伤功能，实现免疫
Isolation of Human and Mouse Hematopoietic Stem Cells
. For clinical applications HSC derived from umbilical cord blood (UCB) and G-CSF mobilized peripheral blood (PB) have been demonstrated to have several advantages compared to bone marrow; therefore, they are slowly replacing BM as alternative source of stem
案例详情 患者男，65 岁，于 2020 年 11 月 22 日来我院体检。 心电图检查：1、窦性心律，2、正常心电图。实验室检查：肝功能及肾功能正常，血糖 6.23mmoL/L，甘油三酯 2.75mmoL/L，胆固醇及高密度脂蛋白胆固醇正常，乙肝五项都阴性，血常规及尿常规都正常。所查的两项肿瘤标志物中唯独甲胎蛋白异常升高。 按照常理，这么高的甲胎蛋白应差不多是肝癌了吧！ 进一步诊查 然而，该体检者的肝脏超声结果却未发现有占位性病变。 1. 彩色多普勒超声 (泌尿系统、肝胆脾 + 双肾、甲状
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