- 询价
- 近岸蛋白(Novoprotein)
- 中国
- DC054
- 2025年11月06日
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- 英文名：
Human CXCL10 (诊断原料,肿瘤标志物）
Recombinant Human CXCL10
Catalog #: DC054 Derived From: E.coli
Description:
Recombinant Human C-X-C Motif Chemokine 10/CXCL10 is produced by E.coli expression system and the target gene encoding Val22-Pro98 is expressed.
Accession: P02778
Names(Known as):C-X-C Motif Chemokine 10; 10 kDa Interferon Gamma-Induced Protein; Gamma-IP10; IP-10; Small-Inducible Cytokine B10; CXCL10; INP10; SCYB10
Quality Control:
Mol Mass: 8.6kDa AP Mol Mass: 13kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of PBS, PH7.4.
Shipping:
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Ion-exchange chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
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文献和实验Analysis of CXCR3 and Atypical Variant Expression and Signalling in Human T Lymphocytes
lymphocytes and binds three pro-inflammatory, interferon-γ-inducible chemokines: monokine induced by IFN-γ (Mig/CXCL9), IFN-γ-induced protein-10 (IP-10/CXCL10) and IFN-γ-inducible T-cell α-chemoattractant (I-TAC/CXCL11). CXCR3 and its agonists are involved
案例详情 患者男，65 岁，于 2020 年 11 月 22 日来我院体检。 心电图检查：1、窦性心律，2、正常心电图。实验室检查：肝功能及肾功能正常，血糖 6.23mmoL/L，甘油三酯 2.75mmoL/L，胆固醇及高密度脂蛋白胆固醇正常，乙肝五项都阴性，血常规及尿常规都正常。所查的两项肿瘤标志物中唯独甲胎蛋白异常升高。 按照常理，这么高的甲胎蛋白应差不多是肝癌了吧！ 进一步诊查 然而，该体检者的肝脏超声结果却未发现有占位性病变。 1. 彩色多普勒超声 (泌尿系统、肝胆脾 + 双肾、甲状
酰胺酶(GLS)、尿苷磷酸化酶 1(UPase1)、组氨酸脱羧酶(HDC)、脂肪酸合成酶(FASN)和鸟氨酸脱羧酶(ODC)，它们广泛参与食管癌相关的肿瘤代谢过程，其中 PYCR2 和 UPase1 被首次发现在食管癌中异常改变。研究结果表明脯氨酸生物合成，谷氨酸代谢，尿苷代谢，组氨酸代谢，脂肪酸合成，多胺生物合成等代谢通路在食管癌组织中发生了显著变化。这些癌症代谢相关信息有助于增加对癌症代谢重编程的理解。 基于 AFADESI-MSI 技术的空间分辨原位代谢组学方法，不仅可验证肿瘤原位标志物的可
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