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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C/-80°C
- 保质期:
12个月
- 英文名:
Recombinant Human Integrin alpha-5(ITGA5)
- 库存:
4
- 供应商:
上海禾午生物科技有限公司
- 规格:
20ug/100ug/1mg
产品详情
纯度:Greater than 90% as determined by SDS-PAGE.
内毒素:Less than 1.0 EU/μg as determined by LAL method.
生物活性:The ED50 as determined by its ability to bind Human NovoNectin in functional ELISA is less than 50 ug/ml.
基因名:ITGA5
Uniprot No.:P08648
别名:CD49 antigen-like family member E; CD49e; Fibronectin receptor subunit alpha; Fibronectin receptor; alpha subunit; FNRA; Integrin alpha 5 (fibronectin receptor alpha); Integrin alpha-5; Integrin alpha-5 light chain; Integrin alpha-F; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide); ITA5_HUMAN; Itga5; Very late activation protein 5; alpha subunit; VLA-5; VLA5; VLA5A
种属:Homo sapiens (Human)
蛋白长度:Partial
来源:Mammalian cell
分子量:105.11 kDa
表达区域:42-995aa
蛋白标签:C-terminal 6xHis-tagged
产品提供形式:Liquid or Lyophilized powder
功能:整合素-5/ β -1 (ITGA5:ITGB1)是纤维连接蛋白和纤维蛋白原的受体。它能识别配体中的R-G-D序列。ITGA5:ITGB1通过一个与经典配体结合位点(site 1)不同的位点(site 2)与PLA2G2A结合,诱导整合素构象改变,增强配体与位点1的结合。ITGA5:ITGB1作为纤维蛋白1 (FBN1)的受体,介导r - g -d依赖性细胞粘附FBN1。ITGA5:ITGB1是IL1B的受体,结合对IL1B信号转导至关重要。ITGA5:ITGB3是可溶性CD40LG的受体,是CD40/CD40LG信号转导所必需的。(微生物感染)整合素ITGA5:ITGB1作为人偏肺病毒的受体(微生物感染)整合素ITGA2:ITGB1作为人细小病毒B19的受体;(微生物感染)在HIV-1感染的情况下,与细胞外病毒Tat蛋白的相互作用似乎可以增强卡波西氏肉瘤病变中的血管生成。
更多活性蛋白请浏览上海禾午生物科技有限公司
上海禾午生物科技有限公司 提供重组蛋白生产服务 His、GST、MBP等多种表达方式同时进行,确保获得蛋白
蛋白表达与纯化服务 纯化的蛋白经过ELISA,Western-blot,或者其它生物活性验证 标签切除 测序报告
上海禾午生物科技有限公司是一家生物高新技术企业,产品覆盖分子生物学、细胞生物学、生物学试剂、标准物质,等领域。以研发、销售为核心致力于生命科学产品。已与全国各大科研院校、医院、企业以及国外一些科研机构有良好的合作关系。
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