- 询价
- 禾午生物
- 国产
- AA10159
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C/-80°C
- 保质期：
12个月
- 英文名：
Recombinant Human Insulin-like growth factor-binding protein 3 protein(IGFBP3)
- 库存：
4
- 供应商：
上海禾午生物科技有限公司
- 规格：
20ug/100ug/1mg
产品详情
纯度：>98% as determined by SDS-PAGE and HPLC.
内毒素：Less than 1.0 EU/μg as determined by LAL method.
生物活性：Fully biologically active when compared to standard. The ED50 as determined by inhibiting IGF-II induced proliferation of serum free human MCF-7 cells is less than 200 ng/ml, corresponding to a specific activity of >5.0x103 IU/mg in the presence of 15 ng/ml of rHuIGF-II.
基因名：IGFBP3
Uniprot No.：P17936
别名：Acid stable subunit of the 140 K IGF complex; Binding protein 29; Binding protein 53; BP 53; BP53; Growth hormone dependent binding protein; IBP 3; IBP-3; IBP3; IBP3_HUMAN; IGF binding protein 3; IGF-binding protein 3; IGFBP 3; IGFBP-3; IGFBP3; Insulin Like Growth Factor Binding Protein 3; Insulin-like growth factor binding protein 3 precursor; Insulin-like growth factor-binding protein 3
种属：Homo sapiens (Human)
蛋白长度：Full Length of Mature Protein
来源：E.Coli
分子量：28.8 kDa
表达区域：28-291aa
蛋白标签：Tag-Free
产品提供形式：Liquid or Lyophilized powder
功能：igf结合蛋白可延长igf的半衰期，并可抑制或刺激igf在细胞培养中的促生长作用。它们改变了igf与其细胞表面受体的相互作用。其受体TMEM219/IGFBP-3R也显示igf独立的抗增殖和凋亡作用。抑制人胰岛素对胰岛素敏感性的积极作用。促进睾丸生殖细胞凋亡。
更多活性蛋白请浏览上海禾午生物科技有限公司
上海禾午生物科技有限公司 提供重组蛋白生产服务His、GST、MBP等多种表达方式同时进行，确保获得蛋白
蛋白表达与纯化服务 纯化的蛋白经过ELISA，Western-blot，或者其它生物活性验证标签切除测序报告
上海禾午生物科技有限公司是一家生物高新技术企业，产品覆盖分子生物学、细胞生物学、生物学试剂、标准物质，等领域。以研发、销售为核心致力于生命科学产品。已与全国各大科研院校、医院、企业以及国外一些科研机构有良好的合作关系。
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文献和实验Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
The insulin-like growth factor-binding proteins (IGFBPs) are carrier proteins that are present in all extracellular fluids (1 ). Similarly, insulin-like growth factor-I (IGF-I) and -II are synthesized by connective tissue cells
Methods for Producing Recombinant Human Cellular Retinaldehyde-Binding Protein
The cellular retinaldehyde-binding protein (CRALBP) is expressed at high levels in vertebrate visual trssue, where it may serve to modulate the interaction of 11-cis -retinol with visual-cycle enzymes in the retinal pigment epithelium (RPE
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