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- 保存条件:
-20°C/-80°C
- 保质期:
12个月
- 英文名:
Recombinant Human Fibroblast growth factor 1(FGF1)
- 库存:
4
- 供应商:
上海禾午生物科技有限公司
- 规格:
20ug/100ug/1mg
产品详情
纯度:Greater than 95% as determined by SDS-PAGE.
内毒素:Less than 1.0 EU/μg as determined by LAL method.
生物活性:The ED50 as determined in a cell proliferation assay using BALB/c 3T3 cells is less than 5 ng/ml.
基因名:FGF1
Uniprot No.:P05230
别名:Acidic fibroblast growth factor; aFGF; Beta endothelial cell growth factor; Beta-endothelial cell growth factor; ECGF; ECGF beta; ECGF-beta; ECGFA; ECGFB; Endothelial Cell Growth Factor alpha; Endothelial Cell Growth Factor beta; FGF 1; FGF alpha; Fgf1; FGF1_HUMAN; FGFA; Fibroblast Growth Factor 1 Acidic; Fibroblast growth factor 1; GLIO703; HBGF 1; HBGF-1; HBGF1; Heparin binding growth factor 1; Heparin binding growth factor 1 precursor; Heparin-binding growth factor 1
种属:Homo sapiens (Human)
蛋白长度:Full Length of Mature Protein
来源:E.coli
分子量:15.9 kDa
表达区域:16-155aa
蛋白标签:Tag-Free
产品提供形式:Liquid or Lyophilized powder
功能:在细胞生存、细胞分裂、血管生成、细胞分化和细胞迁移的调节中发挥重要作用。体外作为有丝分裂原的功能。作为FGFR1和整合素的配体。在肝素存在的情况下与FGFR1结合,导致FGFR1二聚并通过酪氨酸残基上的连续自磷酸化激活,酪氨酸残基作为相互作用蛋白的对接位点,导致多个信号级联的激活。与整合素ITGAV结合:ITGB3。它与整合素的结合,随后与整合素和FGFR1形成的三元复合物,以及PTPN11的招募对FGF1信号转导至关重要。诱导FGFR1、FRS2、MAPK3/ERK1、MAPK1/ERK2和AKT1的磷酸化和激活。可以诱导血管生成。
更多活性蛋白请浏览上海禾午生物科技有限公司
上海禾午生物科技有限公司 提供重组蛋白生产服务 His、GST、MBP等多种表达方式同时进行,确保获得蛋白
蛋白表达与纯化服务 纯化的蛋白经过ELISA,Western-blot,或者其它生物活性验证 标签切除 测序报告
上海禾午生物科技有限公司是一家生物高新技术企业,产品覆盖分子生物学、细胞生物学、生物学试剂、标准物质,等领域。以研发、销售为核心致力于生命科学产品。已与全国各大科研院校、医院、企业以及国外一些科研机构有良好的合作关系。
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