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Recombinant Human Glial cell line-derived neurotrophic factor protein(GDNF)活性蛋白
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C/-80°C
- 保质期:
12个月
- 英文名:
Recombinant Human Brain-derived neurotrophic factor(BDNF)
- 库存:
4
- 供应商:
上海禾午生物科技有限公司
- 规格:
20ug/100ug/1mg
产品详情
纯度:Greater than 95% as determined by SDS-PAGE.
内毒素:Less than 1.0 EU/μg as determined by LAL method.
生物活性:The ED50 as determined by its ability to bind Human TrkB in functional ELISA is less than 5 ug/ml.
基因名:BDNF
Uniprot No.:P23560
别名:Abrineurin; ANON2; BDNF; BDNF_HUMAN; Brain Derived Neurotrophic Factor; Brain-derived neurotrophic factor; BULN2; MGC34632; Neurotrophin
种属:Homo sapiens (Human)
蛋白长度:Full Length of Mature Protein
来源:E.coli
分子量:13 kDa
表达区域:129-247aa
蛋白标签:Tag-Free
产品提供形式:Liquid or Lyophilized powder
功能:激活NTRK2下游信号通路的重要信号分子。在发育过程中,促进周围和中枢神经系统中选定的神经元群体的生存和分化。参与轴突生长,寻径和树突生长和形态的调节。成年中枢神经系统许多区域突触传递和可塑性的主要调节器。BDNF的多功能性被强调为其对一系列适应性神经元反应的贡献,包括长期电位增强(LTP),长期抑郁(LTD),某些形式的短期突触可塑性,以及内在神经元兴奋性的稳态调节。激活NTRK2下游信号通路的重要信号分子。通过由NGFR和SORCS2形成的异二聚体受体激活信号级联。NGFR和SORCS2信号通路在突触可塑性和长期抑郁(LTD)中发挥作用。与NGFR和SORCS2结合可促进神经元凋亡。促进神经元生长锥塌陷。
更多活性蛋白请浏览上海禾午生物科技有限公司
上海禾午生物科技有限公司 提供重组蛋白生产服务 His、GST、MBP等多种表达方式同时进行,确保获得蛋白
蛋白表达与纯化服务 纯化的蛋白经过ELISA,Western-blot,或者其它生物活性验证 标签切除 测序报告
上海禾午生物科技有限公司是一家生物高新技术企业,产品覆盖分子生物学、细胞生物学、生物学试剂、标准物质,等领域。以研发、销售为核心致力于生命科学产品。已与全国各大科研院校、医院、企业以及国外一些科研机构有良好的合作关系。
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文献和实验Production of Recombinant Neurotrophic Factors
factor (NGF), and its related protein family members, brainderived neurotrophic factor (BDNF or NT-2), and neurotrophin3 (NT.-3). The potential of producing mg and larger quantities of these agents will expedite our understanding of their functions
Expression of Neurotrophic Factors such as GDNF in the E. coli System
Neurotrophic factors play an essential role in the growth, survival, and differentiation of neurons in the nervous system. Several well-characterized neurotrophic factors, such as nerve growth factor (NGF), brain-derived
Neural Differentiation of Human Adipose Tissue-Derived Stem Cells
) chemical induction, and neurosphere formation in combination with the cytokines, such as brain-derived neurotrophic factor (BDNF) and basic fibroblast growth factor (bFGF). For in vivo neurogenic induction, ASCs are treated with BDNF and bFGF to form
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