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- MedChemExpress(MCE)
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- HY-W006629
- 2025年12月05日
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- 文献和实验
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- 保存条件：
4°C, sealed storage, away from moisture
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
481704-21-6
- 规格：
1 g/5 g/10 g/25 g/100 g
| 规格： | 1 g | 产品价格： | ￥101.0 |
|---|---|---|---|
| 规格： | 5 g | 产品价格： | ￥316.0 |
| 规格： | 10 g | 产品价格： | ￥572.0 |
| 规格： | 25 g | 产品价格： | ￥1204.0 |
| 规格： | 100 g | 产品价格： | ￥4812.0 |
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tans-4-Hydroxy-D-proline methyl ester hydrochloride
CAS No. : 481704-21-6
MCE 国际站：tans-4-Hydroxy-D-proline methyl ester hydrochloride
产品活性：tans-4-Hydroxy-D-proline methyl ester hydrochloride 是不可降解 (non-cleavable) 的 ADC linker，用于合成抗体偶联活性分子 (ADCs)。tans-4-Hydroxy-D-proline methyl ester hydrochloride 也是一个基于烷基链 (alkyl chain) 的 PROTAC linker，可用于合成 PROTAC。
研究领域：Antibody-drug Conjugate/ADC Related | PROTAC
作用靶点：ADC Linker | PROTAC Linkers
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
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文献和实验Metabolic Labeling of Prenyl and Carboxyl‐Methyl Groups
that are incorporated as prenoids??e.g., farnesyl and geranylgeranyl. Carboxy?methylation often accompanies prenylation. The methyl group can be labeled using [3 H?methyl]methionine.
Radioligand Binding Assays for the Glycine Site on N‐Methyl‐D‐Aspartate Receptors
., Mutel, V., Trube, G., Malherbe, P., Kew, J.N., Mohacsi, E., Heitz, M.P., and Kemp, J.A. 1997. Ro 25‐6981, a highly potent and selective blocker of N‐methyl‐D‐aspartate receptors containing the NR2B subunit: Characterization in vitro. J. Pharmacol. Exp
Synthesis of Peptidomimetic Conjugates of Cyclic Nucleoside Phosphonates
) (D )‐Serine methyl ester hydrochloride (Aldrich) (L )‐Serine isopropyl ester hydrochloride (Aurora Building Blocks)
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