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货期:询盘
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MedChemExpress LLC
- CAS号:
2862800-15-3
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询盘
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Colistin adjuvant-1
CAS No. : 2862800-15-3
MCE 国际站:Colistin adjuvant-1
产品活性:Colistin adjuvant-1 是一种粘菌素佐剂 (colistin adjuvant),对革兰氏阴性细菌显示出增强的粘菌素增强活性。Colistin adjuvant-1 抑制 NF-κB 的 IC50 为 0.209 μM。
研究领域:Anti-infection | NF-κB
作用靶点:Bacterial | NF-κB
In Vitro: Colistin adjuvant-1 (compound 13) inhibits a panel of additional colistin-resistant strains of K. pneumoniae and A. baumannii, including strains harboring the mcr-1 gene, and also determined activity against colistin-resistant strains of P. aeruginosa.
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文献和实验, Inc. ), the latter being less hazardous than the first. 1st injection: 15 - 50 ug Antigen in 200 ul adjuvant, injected subcutaneously. 2nd injection: 2 weeks later; boost with 15 - 50 ug of Antigen in adjuvant. (If time permits, boost again a month later). 7 - 10 days
Polyclonal and Monoclonal Antibodies(克隆和克隆抗体)
either of the two following adjuvants with success: Freund adjuvant and MPL+TDM adjuvant ( RIBI ImmunoChem Research, Inc. ), the latter being less hazardous than the first. 1) 1st injection: 15 - 50 ug Antigen in 200 ul adjuvant, injected subcutaneously. 2) 2nd
又称水油乳化佐剂。是由J.夫罗因德(1942)所创制的、以诱发实验动物强烈免疫反应为目的的最常用佐剂。由矿物油(例如BayolF)85%同表面活性剂(例如ArlacelA)15%混合而成,称为不完全佐剂(incomplete adjuvant),再加入分枝杆菌(结核菌等)的加热死菌(0.1—1毫克/毫升)则称完全佐剂(complete adjuvant)。在实际使用时,加抗原悬浮液和等量的佐剂,搅拌后作为水油乳剂(water-in-oil emulsion)注射于皮下、脚心、腹腔
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