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- 重组小鼠 gp130 / IL6ST / CD130 蛋白
- 湖北武汉
- 2025年07月16日
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强耀生物
| 规格 | 20ug |
| 编号 | CZDB-001 |
| 分子别称 | Ac1055, Gp130, Il-6rb |
| 分子种属 | Mouse |
| 表达标签 | His，S |
| 表达宿主 | E. coli |
| 浓度 | > 95 % as determined by SDS-PAGE |
| 缓冲液 | Lyophilized from sterile PBS, pH 7.4 |
| 存储条件 | -70°C，应避免反复冻融。 |
| 基本描述 | Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta or CD130) is a transmembrane protein which is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events. |
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文献和实验Characterization of HIV gp120 Envelope Glycoprotein by Lectin Analysis
The envelope glycoprotein gp120 of the human immunodeficiency virus (HIV), the causative agent of AIDS, contains approx 24 potential sites for N -glycosylation (Asn-X-Ser/Thr, X≠Pro) (1 ), all of which are utilized
网络 第二节 X 2 检验 X 2 （称卡方）检验用途较广，但主要用于检验两个或两个以上样本率或构成比之间差别的显著性，也可检验两类事物之间是否存在一定的关系。 一、两个率的比较 （一）X 2 检验的基本公式 下页
相对数与X2 检验 调查或实验搜集来的原始资料,经过汇总之后得到的小计或总计数值称为绝对数(即总量指标)。如发病人次数、医院收容人数、治愈人数等。总量指标反映一定条件下某种事物的规模或水平,是计划或总结工作的依据,同时,又是计算相对数与平均数的基础,但是绝对数往往不便于比较,因此在实际工作中还必须计算相对数与平均数。 第一节 相对数 一、相对数及其意义 相对数是两个有关的绝对数之比,通常用百分比、千分比或万分比等表示
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