Anti-NECAB3 Polyclonal Antibod

Anti-NECAB3 Polyclonal Antibody


产品简介

英文名称	Anti-NECAB3 Polyclonal Antibody
靶标	VPS37B
别名	NECAB3;APBA2BP;EFCBP3;NIP1;STIP3;SYTIP2;XB51;dJ63M2.4;dJ63M2.5
宿主	Rabbit
稀释比例	WB 1:1000-3000. IHC 1:50-200.
Gene ID	63941
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q96P71
蛋白分子量	22/41/44kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	A synthetic peptide of NECAB3
亚型	IgG
纯化方法	Octanoic acid-ammonium sulfate precipitation
背景资料	The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Public Immunogen Range	270-320/396aa
克隆类型	Polyclonal Antibody
交叉反应	Human
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with NECAB3 antibody diluted at 1:2000;Lane:U251,HepG2,T-47d,HeLa,PC-3M-IE8,U-87,LO2

Immunohistochemistry of paraffin-embedded Human colorectal cancer using NECAB3 antibody diluted at 1:100