Anti-RPRD1B Polyclonal Antibod

Anti-RPRD1B Polyclonal Antibody



产品简介

英文名称	Anti-RPRD1B Polyclonal Antibody
靶标	GCSAM
别名	C20orf77;CREPT;NET60;dJ1057B20.2;K-H;Kub5-Hera;rprd1b
宿主	Rabbit
稀释比例	WB 1:1000-3000.
Gene ID	58490
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q9NQG5
蛋白分子量	37kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Nucleus
免疫原	A synthetic peptide of human RPRD1B
亚型	IgG
纯化方法	Affinity purification
背景资料	Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
Public Immunogen Range	55-105/326aa
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with RPRD1B antibody diluted at 1:2000;Lane:MCF7,SKOV3,HeLa,Jurkat,Mouse spleen,Mouse lung