Anti-ALOX5 Polyclonal Antibody

Anti-ALOX5 Polyclonal Antibody


产品简介

英文名称	Anti-ALOX5 Polyclonal Antibody
靶标	ALOX5
别名	5-LO;5-LOX;5LPG;LOG5
宿主	Rabbit
稀释比例	WB 1:1000-3000. IHC 1:50-200.
Gene ID	240
保存	Store at -35°C. Avoid freeze / thaw cycles.
Swiss Prot	P09917
蛋白分子量	56/61/72/75/78kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.18.
亚细胞定位	Nucleus
免疫原	A synthetic peptide of human ALOX5
亚型	IgG
纯化方法	Affinity purification
背景资料	This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Public Immunogen Range	15-65/674
克隆类型	Polyclonal Antibody
交叉反应	Human Predicted:Hamster Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with ALOX5 antibody diluted at 1:2000;Lane:Raji,HMC1

Immunohistochemistry of paraffin-embedded Human tonsil with ALOX5 antibody diluted at 1:100