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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human MHC class I polypeptide-related sequence A (MICA), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Human MHC class I polypeptide-related sequence A (MICA), partial品名简称:
Recombinant Human MICA protein, partial货号:
CSB-EP013806HU规格:
20μg价格:
1836LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 85% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
MICAUniprot No.:
Q29983别名:
MIC-A种属:
Homo sapiens (Human)蛋白长度:
Partial来源:
E.coli分子量:
39.6 kDa表达区域:
24-307aa氨基酸序列:
EPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW蛋白标签:
N-terminal 6xHis-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
13-23 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
/功能2:
/文献:
/研究领域:
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文献和实验Molecular Typing of the MHC Class I Chain-Related Gene Locus
The human major histocompatibility complex (MHC) class I chain-related genes A and B (MICA and MICB ) are located within the human leukocyte antigen (HLA) class I region of chromosome 6 (1 ). Their organization, expression, and products
实体瘤细胞治疗基础研究的重要方向。人们在对免疫过程的研究中发现并证实,特异性 T 细胞激活的前提条件是 T 细胞受体(TCR)和 MHC-肽复合物结合,因此细胞毒性 T 细胞(CTL)表位在其中起着至关重要的作用。CTL 表位 (CTL epitope) 一般长度为 8-10 个氨基酸,是蛋白抗原经抗原递呈细胞(Antigen process cell,APC)加工处理,随后与 MHC-Ⅰ类分子结合并最终递呈给 TCR 识别,引起有效免疫应答的短肽。CTL 表位的筛选和鉴定在特异性 T 细胞应答
Assessing Antigen-Specific CD8+ CTL Responses in Humans
recognized by NP-specific CTL in a major histocompatability complex (MHC) class I restricted manner (5 ,6 ). Bjorkman et al. (6 ,7 ) subsequently resolved the structure of the human class I molecule HLA-A2 by x-ray crystallography and provided evidence
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