- ￥1855
- 翌圣生物（Yeasen）
- 90146ES10
- 上海
- 2025年10月22日
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
一年
- 保存条件：
-20 ºC保存
- 供应商：
翌圣生物科技(上海)股份有限公司
- 库存：
大量
- 英文名：
Recombinant Mouse Interleukin-6 (Mouse IL-6)
- 规格：
10μg
| Product Name | Cat# | Size | Price（¥） |
| Recombinant Mouse IL-6 Protein | 90146ES10 | 10 μg | 1855.00 |
| 90146ES60 | 100 μg | 7865.00 | |
| 90146ES76 | 500 μg | 20425.00 |
Product Description
Interleukin 6 (IL-6), which was originally identified as a B-cell differentiation factor, is now known to be a multifunctional cytokine that regulates the immune response, hematopoiesis, the acute phase response, and inflammation. IL-6 is a pleiotropic, alpha -helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. It also induces myeloma and plasmacytoma growth. And it is a pleiotropic cytokine that not only affects the immune system, but also acts in other biological systems and many physiological events in various organs. In a target cell, IL-6 can simultaneously generate functionally distinct or sometimes contradictory signals through its receptor complex, IL-6Ralpha and gp130.
Product Properties
| Synonyms | Interleukin-6, IL-6, B-cell differentiation factor, B-cell stimulatory factor 2, BSF2; BSF-2, CDF, CTL differentiation factor, HSF, IFNB2, IFN-beta-2, Interferon beta-2, interleukin BSF-2, MGI-2A. |
| Accession | P08505 |
| GeneID | 16193 |
| Source | E.coli-derived mouse IL-6 protein, Phe25-Thr211, with an N-terminal Met. |
| Molecular Weight | Approximately 21.7 kDa. |
| AA Sequence | MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT |
| Tag | None |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity | > 97% by SDS-PAGE and HPLC analyses. |
| Biological Activity | The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is less than 0.02 ng/mL, corresponding to a specific activity of > 5 × 107 IU/mg. Fully biologically active when compared to standard. |
| Endotoxin | < 1.0 EU per 1μg of the protein by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in 30 mM Acetic Acid, pH 3.0, 150 mM NaCl, 5% Trehalose, 0.02% Tween-20. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ for 1 year.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Avoid repeated freeze-thaw cycles.
2.For your safety and health, please wear lab coats and disposable gloves for operation.
3.For research use only.
HB221031
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