Mouse IL-4 重组小鼠白细胞介素-4(小鼠白介素-4)

Mouse IL-4 重组小鼠白细胞介素-4(小鼠白介素-4

)
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  • ¥535
  • 翌圣生物(Yeasen)已认证
  • 90144ES08
  • 上海
  • 2025年10月22日
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    • 详细信息
    • 技术资料
    • 保质期

      有效期1年

    • 保存条件

      -20℃至-80℃保存

    • 供应商

      翌圣生物科技(上海)股份有限公司

    • 库存

      大量

    • 英文名

      Recombinant Mouse Interleukin-4 (Mouse IL-4)

    • 规格

      5μg

    Product Information

     

    Product Name

    Cat#

    Size

    Price(¥

    Recombinant Mouse Interleukin-4 (Mouse IL-4)

    90144ES08

    5 μg

    815.00

    90144ES60

    100 μg

    8515.00

    90144ES76

    500 μg

    22115.00

     

    Product Description

     

    Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a pleiotropic cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by by mast cells, activated T cells and bone marrow stromal cells. Mature human IL-4 shares 55%, 39% and 43% aa sequence identity with bovine, mouse, and rat IL-4, respectively.It is a potent cytokine produced by T cells and to a lesser extent by tumor-associated natural killer cells, basophils, and mast cells. IL-4 is a differentiation factor for transforming growth factor-beta secreting Th3. And IL-4 activates two distinct signalling pathways through tyrosine phosphorylation of Stat6, a signal transducer and activator of transcription, and of a 170K protein called 4PS.

     

    Product Properties

     Mouse IL-4 重组小鼠白细胞介素-4(小鼠白介素-4

    Synonyms

    Interleukin-4, IL-4, BSF-1, BCDF, IL4E12, Pitrakinra

    Accession

    P07750

    GeneID

    16189

    Source

    E.coli-derived mouse IL-1alpha protein, His21-Ser140, with an N-terminal Met.

    Molecular Weight

    Approximately 13.5 kDa.

    AA Sequence

    MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    > 97% by SDS-PAGE and HPLC analyses.

    Biological Activity

    The ED50 as determined by the dose-dependant prolifiration of Murine HT-2 cells is less then 2 ng/mL, corresponding to a Specific Activity of > 5 × 105 IU/mg. Fully biologically active when compared to standard.

    Endotoxin

    < 1.0 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

     

    Avoid repeated freeze-thaw cycles.

    For your safety and health, please wear lab coats and disposable gloves for operation.

    For research use only.

     

    HB220210

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