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- 详细信息
- 技术资料
- 保质期:
有效期1年
- 保存条件:
-20℃至-80℃保存
- 供应商:
翌圣生物科技(上海)股份有限公司
- 库存:
大量
- 英文名:
Recombinant Mouse Interleukin-4 (Mouse IL-4)
- 规格:
5μg
Product Information
| Product Name |
Cat# |
Size |
Price(¥) |
| Recombinant Mouse Interleukin-4 (Mouse IL-4) |
90144ES08 |
5 μg |
815.00 |
| 90144ES60 |
100 μg |
8515.00 |
|
| 90144ES76 |
500 μg |
22115.00 |
Product Description
Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a pleiotropic cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by by mast cells, activated T cells and bone marrow stromal cells. Mature human IL-4 shares 55%, 39% and 43% aa sequence identity with bovine, mouse, and rat IL-4, respectively.It is a potent cytokine produced by T cells and to a lesser extent by tumor-associated natural killer cells, basophils, and mast cells. IL-4 is a differentiation factor for transforming growth factor-beta secreting Th3. And IL-4 activates two distinct signalling pathways through tyrosine phosphorylation of Stat6, a signal transducer and activator of transcription, and of a 170K protein called 4PS.
Product Properties

| Synonyms |
Interleukin-4, IL-4, BSF-1, BCDF, IL4E12, Pitrakinra |
| Accession |
|
| GeneID |
|
| Source |
E.coli-derived mouse IL-1alpha protein, His21-Ser140, with an N-terminal Met. |
| Molecular Weight |
Approximately 13.5 kDa. |
| AA Sequence |
MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S |
| Tag |
None |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity |
> 97% by SDS-PAGE and HPLC analyses. |
| Biological Activity |
The ED50 as determined by the dose-dependant prolifiration of Murine HT-2 cells is less then 2 ng/mL, corresponding to a Specific Activity of > 5 × 105 IU/mg. Fully biologically active when compared to standard. |
| Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
| Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
Avoid repeated freeze-thaw cycles.
For your safety and health, please wear lab coats and disposable gloves for operation.
For research use only.
HB220210
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