- ￥985
- 翌圣生物（Yeasen）
- 92549ES60
- 上海
- 2026年04月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
有效期1年
- 保存条件：
-20℃至-80℃保存
- 供应商：
翌圣生物科技（上海）股份有限公司
- 库存：
大量
- 英文名：
Recombinant Human Vitronectin,His (Human VTN,His)
- 规格：
100ug
Product Information
| Product Name |
Cat# |
Size |
Price（¥） |
| Recombinant Human Vitronectin,His (Human VTN,His) |
92549ES60 |
100 μg |
1,885 |
| 92549ES80 |
1 mg |
13,185 |
Product Description
Vitronectin is a secreted glycoprotein that is synthesized in the liver. It circulates primarily in monomeric form, but can undergo conformational change to a structure that forms disulfide-linked multimers. The multimeric vitronectin can efficiently bind to, and incorporate into, the extracellular matrix. Within the matrix, vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Additionally, recombinant vitronectin can function as a chemically-defined matrix component in human embryonic stem cell renewal media.
Product Properties
| Synonyms |
V75 ; Vitronectin ; VN |
| Accession |
P04004 |
| Source |
HEK293 Cells-derived human VTN protein, Met1-Leu478 with His tag at the C-terminus. |
| Molecular Weight |
Approximately 53.7 kDa. As a result of glycosylation, it migrates as an approximately 68.1 kDa band in SDS-PAGE under reducing conditions. |
| AA Sequence |
MAPLRPLLIL ALLAWVALAD QESCKGRCTE GFNVDKKCQC DELCSYYQSC CTDYTAECKP QVTRGDVFTM PEDEYTVYDD GEEKNNATVH EQVGGPSLTS DLQAQSKGNP EQTPVLKPEE EAPAPEVGAS KPEGIDSRPE TLHPGRPQPP AEEELCSGKP FDAFTDLKNG SLFAFRGQYC YELDEKAVRP GYPKLIRDVW GIEGPIDAAF TRINCQGKTY LFKGSQYWRF EDGVLDPDYP RNISDGFDGI PDNVDAALAL PAHSYSGRER VYFFKGKQYW EYQFQHQPSQ EECEGSSLSA VFEHFAMMQR DSWEDIFELL FWGRTSAGTR QPQFISRDWH GVPGQVDAAM AGRIYISGMA PRPSLAKKQR FRHRNRKGYR SQRGHSRGRN QNSRRPSRAT WLSLFSSEES NLGANNYDDY RMDWLVPATC EPIQSVFFFS GDKYYRVNLR TRRVDTVDPP YPRSIAQYWL GCPAPGHL |
| Tag |
His |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity |
> 90% by SDS-PAGE. |
| Biological Activity |
Measured by the ability of the immobilized protein to support the adhesion of DU145 human prostate carcinoma cells. When cells are added to Vitronectin-coated plates (10 μg/mL and 100 μL/well), approximately >40% cells will adhere specifically after 30 minutes at 37℃. |
| Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
| Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only.
HB220415
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Microarray Approaches for Analysis of Cell Cycle Regulatory Genes
genes is also known to play an important role in disease states such as genomic instability and cancer. For instance, p53, a cell cycle regulatory transcription factor, is also one of the most commonly mutated tumor-suppressor genes in human cancer
(9): 1245–53. doi:10.1101/gr.6406307. PMID 17690206. ^ Bertone P, Stolc V, Royce TE, Rozowsky JS, Urban AE, Zhu X, Rinn JL, Tongprasit W, Samanta M, Weissman S, Gerstein M, Snyder M (December 2004). "Global identification of human transcribed sequences
