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- 2025年07月16日
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文献和实验Expression and Dimerization of Hepatitis C Virus Core Protein in E. coli
Hepatitis C virus (HCV) is a positive-stranded RNA virus with a genome size of about 9–10 kb. The genome of this virus encodes a polyprotein with a length of over 3000 amino acids. This polyprotein is cleaved by cellular and viral proteases
Nomenclature and Numbering of the Hepatitis C Virus
International standardization and coordination of the nomenclature of variants of hepatitis C virus (HCV) is increasingly needed as more is discovered about the scale of HCV-related liver disease and important biological and antigenic
In Vitro Kinetic Profiling of Hepatitis C Virus NS3 Protease Inhibitors by Progress Curve Analysis
Kinetic profiling of drug binding to its target reveals important mechanistic parameters including drug–target residence time. In this chapter, we focus on global progress curve analysis as a convenient method for kinetic profiling. Detailed
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