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- Fabgennix
- GTPCH1-112AP
- 2025年07月11日
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文献和实验A Sensitive Assay for the Enzymatic Activity of GTP Cyclohydrolase I
enzyme in the biosynthetic pathway of BH 4 is GTP cyclohydrolase I (EC 3.5.4.16). Cellular expression of this enzyme is subject to varied and multi-level control that is cell-type specific. For example, the activity of GTP cyclohydrolase I in immune cells
Measurement of Biopterin and the Use of Inhibitors of Biopterin Biosynthesis
(GTP) by three enzymes. GTP cyclohydrolase I converts GTP to dihydroneopterin triphosphate, which is then converted to 6-pyruvoyltetrahydropterin by 6-pyruvoyltetrahydropterin synthase. This second unstable intermediate compound is converted to BH
Secretory Vesicle Swelling by Atomic Force Microscopy
with the known water channel inhibitor Hg2+ is accompanied by a reversible loss in both the basal and GTP-stimulable water entry and vesicle swelling. Introduction of AQP1-specific antibody raised against the carboxy-terminal domain of AQP1 blocked GTP-stimulable
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