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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
TC-1
- 库存：
1x10^6/瓶/支
- 供应商：
上海酶研
- 肿瘤类型：
详询
- 细胞类型：
小鼠肺上皮细胞
- ATCC Number：
详询
- 品系：
TC-1
- 组织来源：
小鼠肺上皮细胞
- 相关疾病：
TC-1
- 物种来源：
哺乳动物
- 免疫类型：
详询
- 细胞形态：
贴壁/悬浮
- 是否是肿瘤细胞：
详询
- 器官来源：
小鼠肺上皮细胞
- 运输方式：
顺丰快递
- 年限：
5年
- 生长状态：
生长良好
TC-1/TC-1细胞系/TC-1细胞株/TC-1小鼠肺上皮细胞
Cell line name TC-1 [Mouse lung]
Synonyms TC-1[JHU-1]; Tissue Culture-1
Accession CVCL_4699
Resource Identification Initiative To cite this cell line use: TC-1 [Mouse lung] (RRID:CVCL_4699)
Comments Doubling time: 18.2 hours (PubMed=12559790); 18.5 hours (PubMed=31638243).
Genetic integration: Method=Transduction; Gene=HGNC; 5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_ZW99 (TC-1/A9) CVCL_ZX00 (TC-1/D11) CVCL_ZX01 (TC-1/dB2m)
CVCL_B6PJ (TC-1/E2)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications
PubMed=8548765
Lin K.-Y., Guarnieri F.G., Staveley-O'Carroll K.F., Levitsky H.I., August J.T., Pardoll D.M., Wu T.-C.
Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.
Cancer Res. 56:21-26(1996)
PubMed=12559790; DOI=10.1016/S0264-410x(02)00519-4
Smahel M., Sima P., Ludvikova V., Marinov I., Pokorna D., Vonka V.
Immunisation with modified HPV16 E7 genes against mouse oncogenic TC-1 cell sublines with downregulated expression of MHC class I molecules.
Vaccine 21:1125-1136(2003)
PubMed=31638243; DOI=10.3892/or.2019.7356
Lhotakova K., Grzelak A., Polakova I., Vackova J., Smahel M.
Establishment and characterization of a mouse tumor cell line with irreversible downregulation of MHC class I molecules.
Oncol. Rep. 42:2826-2835(2019)
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文献和实验*发表【中文论文】请标注：由上海酶研生物科技有限公司提供；
*发表【英文论文】请标注：From Shanghai EK-Bioscience Biotechnology Co., Ltd.
a look from the following website just by clicking "Tyrosine Phosphorylation and Dimerization" http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-43F85YV-2&_user=1111158&_coverDate=06%2F29%2F2001&_rdoc=1&_fmt=full&_orig=search
扫描仪中，都采用机械式的二维X，Y线性扫描技术实现，即X，Y方向都采用直线驱动器和直线导轨实现往复运动。此类装置，由于驱动系统的频率限制，驱动器的扫描惯性大，使得扫描效率低，分析时间相当长；并且往复行程长，对直线导轨的精度要求相当高。二、光机结合的二维扫描系统为同样实现生物芯片的二维扫描，我们的实验装置设计如图2，采用了振镜和大数值孔径的远心f-è物镜相结合实现X方向扫描，Y方向的运动仍采用直线驱动器和直线导轨实现。 系统中，对于f-è物镜，满足x＝2fè（è为振镜的摆动角度，f为物镜焦距）的线性
Analysis of RB Action in DNA Damage Checkpoint Response
checkpoint response: (1) transcriptional repression of E2F-regulated genes (cyclin A reporter assay); (2) induction of cell cycle arrest (Brd-U incorporation assay); and (3) inhibition of DNA double-strand break accumulation (phosphorylated-histone H2A.X
技术资料
