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文献和实验Nature 重磅:新发脑胶质瘤疫苗初见成效,瞄准肿瘤「阿喀琉斯之踵」
,发挥抗肿瘤效应。该成果以 A vaccine targeting mutant IDH1 in newly diagnosed glioma 为题发表在最新的 Nature 上 [2]。 图片来源:Nature 研究内容:这是一项靶向 IDH1R132H 的多肽疫苗治疗 III-IV 级(WHO 分级)胶质瘤的安全性、耐受性和免疫原性的多中心 I 期临床研究(NCT02454634)。研究人员筛选了 44 名患者,其中 32 名患者入组参与了临床试验并接受了 IDH-vac 治疗。在这 32 名
Recombinant Protein Production in Yeasts
Recombinant protein production is a multibillion-dollar market. The development of a new product begins with the choice of a production host. While one single perfect host for every protein does not exist, several expression systems ranging
Recombinant Protein Expression in Nicotiana
Recombinant protein pharmaceuticals are now widely used in treatment of chronic diseases, and several recombinant protein subunit vaccines are approved for human and veterinary use. With growing demand for complex protein pharmaceuticals
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