- ￥900 - 1800
- Proteintech
- APC-65055
- 2025年10月13日
- FC
- Rat
- human, mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG2b, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
APC Fluorescent Dye
- 适应物种：
human, mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rat
- 应用范围：
FC
- 靶点：
CD11b
- 抗体英文名：
APC Anti-Mouse CD11b (M1/70)
- 抗体名：
APC Anti-Mouse CD11b (M1/70)
- 规格：
25ug/100ug
| 规格： | 25ug | 产品价格： | ￥900.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥1800.0 |
经过测试的应用
| Positive FC detected in | mouse bone marrow cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.1 ug per 10^6 cells in a 100 µl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
APC-65055 targets CD11b in FC applications and shows reactivity with human, mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | FC |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2b, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | integrin alpha M |
| 别名 | CR3, CR3A, integrin alpha M, Itgam, Ly 40 |
| 计算分子量 | 127 kDa |
| GenBank蛋白编号 | BC156991 |
| 基因名称 | CD11b |
| Gene ID (NCBI) | 16409 |
| RRID | AB_2882958 |
| 偶联类型 | APC Fluorescent Dye |
| 最大激发/发射波长 | 650 nm / 660 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | E9Q604 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | FC | Adv Mater Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease TreatmentAuthors - Yuewen Zhai |
| mouse | FC | Adv Sci (Weinh) Cancer-Associated Fibroblast-Induced Remodeling of Tumor Microenvironment in Recurrent Bladder CancerAuthors - Ting Liang |
| FC | J Nanobiotechnology PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancerAuthors - Chao Wang | |
| FC | Int Immunopharmacol EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosisAuthors - Huiling Zhang | |
ACS Chem Neurosci Novel Perspective on Sevoflurane-Induced Cognitive Dysfunction: Implications of Neuronal SIRPα and Microglial Synaptic RemodelingAuthors - Wei Du | ||
| human,mouse | FC | Cell Death Dis EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsisAuthors - Xuedi Zhang |
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