- ￥900 - 1810
- Proteintech
- APC-65054
- 2025年10月13日
- FC
- Rat
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG2b, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
APC Fluorescent Dye
- 适应物种：
mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rat
- 应用范围：
FC
- 靶点：
CD117/c-Kit
- 抗体英文名：
APC Anti-Mouse CD117/c-Kit (2B8)
- 抗体名：
APC Anti-Mouse CD117/c-Kit (2B8)
- 规格：
25ug/100ug
| 规格： | 25ug | 产品价格： | ￥900.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥1810.0 |
经过测试的应用
| Positive FC detected in | mouse bone marrow cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.4 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
APC-65054 targets CD117/c-Kit in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 经测试反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2b, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | kit oncogene |
| 别名 | Kit, CD117, c KIT, 2B8 |
| GenBank蛋白编号 | BC052457 |
| 基因名称 | CD117 |
| Gene ID (NCBI) | 16590 |
| RRID | AB_2882957 |
| 偶联类型 | APC Fluorescent Dye |
| 最大激发/发射波长 | 650 nm / 660 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P05532 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early haemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628).
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文献和实验中。5. 用无菌 PBS 将上述锥形试管填满（至 50 mL)。介绍样品制备。6. 洗涤。在室温、低速制动条件下，以 300 X g 离心分离试管 10 分钟。7. 裂解红细胞（BD 产品目录号：555899，10 x 溶液。在蒸馏水中使用 1 x 溶液。室温孵育 15 分钟。）8. 将 1x106 PBMC 重悬于 20 μL 染色缓冲液中（PBS 含有 5% 正常人血清）。9. 加入抗体：CD117-BV421 (c-kit)、CD7-BV510、CD57- BV605、CD8-BV650
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