- ￥650 - 1990
- Proteintech
- 65058-1-Ig
- 2025年10月13日
- IF/ICC, FC
- Rat
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG2a, kappa
- 保存条件：
Store at 2-8°C. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rat
- 应用范围：
IF/ICC, FC
- 靶点：
CD31
- 抗体英文名：
Anti-Mouse CD31 (390)
- 抗体名：
Anti-Mouse CD31 (390)
- 规格：
100ug/500ug
| 规格： | 100ug | 产品价格： | ￥650.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥1990.0 |
经过测试的应用
| Positive IF/ICC detected in | bEnd.3 cells |
| Positive FC detected in | mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65058-1-Ig targets CD31 in IF/ICC, FC applications and shows reactivity with mouse samples.
| 经测试应用 | IF/ICC, FC |
| 文献引用应用 | IF |
| 经测试反应性 | mouse |
| 文献引用反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2a, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | platelet/endothelial cell adhesion molecule 1 |
| 别名 | 390, Pecam, PECAM 1, Pecam1, PECAM-1 |
| GenBank蛋白编号 | BC008519 |
| 基因名称 | CD31 |
| Gene ID (NCBI) | 18613 |
| RRID | AB_2918366 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | Q08481 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).
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49e/CD29、CD49f/CD29、CD51/CD29、CD11a/CD18、CD11b/CD18、CD11c/CD18、CD41/CD61、CD51/CD61、CD49f/CD104、CD2、CD4、CD8、CD28、CD31、CD50、CD54、CD56、CD58、CD80、CD102、CD106、CD62L、CD62P、CD62E、CD15、CD15s、CD44等。 （2）B表示CD命名范围中属IGSF结构的分子，如CD79a、CD79b、CD1、CD
网络 二、Ig超家族的特点 （一）Ig超家族的结构特点 Ig超家族成员均含有1～7个Ig样结构域，每个Ig样结构域约含70～110个氨基酸残基。其二级结构是两个各含3～5个反平行β折叠股所形成的β片层（anti-parallel β-pleated sheet)平面，每个反平行β折叠股由5～10个氨基酸残基组成，β
网络 三、CD、粘附分子与Ig超家族的关系 免疫分子的命名根据不同的角度往往有不同的归类和命名，图3-3归纳了人白细胞分化抗原（CD）、粘附分子（AM）、免疫球蛋白超家族（IGSF）、细胞因子受体（CKR）、补体受体（CR）以及主要组织相容性复合体抗原（MHC）等免疫分子命名的相互关系。 （1）A表示CD命名范围中的
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