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- 禾午生物
- 国产
- P35717
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃&-80℃
- 保质期：
3个月~12个月
- 英文名：
pET32a-APP(human)(1-701aa)(723-770aa)-EGFP-6×His
- 库存：
999
- 供应商：
上海禾午生物科技有限公司
- 规格：
干粉&甘油菌
| 启动子 | T7 |
| 复制子 | pBR322 |
| 感受态 | DH5a |
| 培养温度 | 37度 |
| 质粒宿主 | 大肠杆菌 |
| 质粒用途 | 蛋白表达 |
| 片段类型 | ORF |
| 片段物种 | 人 |
| 原核抗性 | Amp |
| 荧光标记 | 绿色 |
| pCMV-SPORT6-Aplf(mouse)(1点突变缺失一段) |
| pETDuet1-Promoter-mcjB-mcjC-mcjD(coli)-T7-msyB-mcjA(coli) |
| pOTB7-DLGAP5(human)(1同义突变) |
| pCR4-TOPO-MECOM(human)(1-374缺失1点突变1点插入) |
| pCMV-SPORT6-CREB3L4(human) |
| pYX-Asc-Lamp1(mouse)(3点缺失) |
| pET32a-APP(human)(1-701aa)(723-770aa)-EGFP-6×His |
| pUC19-Tac-mCherry-FRT-Kan-FRT-1 |
| pCMV-SPORT6-Jarid1a(mouse) |
| pCMV-SPORT6-C5H12orf57(cattle) |
| pCMV-SPORT6-SEC14L2(cattle) |
| pCMV-SPORT6-CDK10(cattle) |
| pCMV-SPORT6-PLPP1(cattle) |
| pCMV-SPORT6-Mbc2(mouse) |
| pCMV-SPORT6-Cd79b(mouse) |
质粒均可提供详细图谱、序列、测序报告。基因合成 载体构建 病毒包装 稳转株构建
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文献和实验APP-Based Transgenic Models: The APP23 Model
transgenic mouse. This paper describes the development and assessment of this human amyloid precursor protein overexpression model. We summarize histopathological and biochemical, cognitive and behavioral observations made in heterozygous APP23 mice
Measuring APP Carboxy-Terminal Fragments
within the Aβ region, precluding its formation. Therefore, modulation of β- and/or γ-secretase activity represents important therapeutic targets. Transgenic mice overexpressing human APP generate detectable levels of APP CTFs and Aβ. We have shown that highly
APP-Based Transgenic Models: The PDAPP Model
mouse to overexpress the human amyloid precursor protein (hAPP) that successfully recapitulated several neuropathological features characteristic of AD. These include Aβ deposition in both diffuse and neuritic plaques, cerebral amyloid angiopathy
技术资料
