- 询价
- Cell Signaling Technology
- 2989
- USA
- 2025年11月21日
- W, IP
- Rabbit
- M,R
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
RANTES Antibody (Rodent Specific)
- 抗原：
synthetic peptide corresponding to residues at the carboxyl terminus of rodent RANTES
- 应用范围：
W, IP
- 宿主：
Rabbit
- 保质期：
详见说明书
- 适应物种：
M,R
- 供应商：
CST
- 库存：
大量
- 级别：
详见MSDS文件
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation
Reactivity Key: M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IP | M (R) | Transfected Only | 10 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | RANTES Antibody (Rodent Specific) detects transfected levels of rodent RANTES. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues at the carboxyl terminus of rodent RANTES. Western Blotting
Western blot analysis of HeLa cells, mock transfected or transfected with mouse RANTES, using RANTES Antibody (Rodent Specific). |
| Background | RANTES/CCL5 (regulated upon activation, T cell expressed and secreted) is a member of the "C-C" or β family of chemokines that induce inflammation and are associated with a number of inflammatory disorders (1,2). RANTES is produced and secreted mainly by CD8+ T cells, macrophages, and platelets, as well as epithelial cells, fibroblasts and some solid tumors (2-7). RANTES acts as a chemoattractant and has other regulatory functions on a number of cell types including monocytes, memory T cells, NK cells, eosinophils, basophils, dendritic cells, and mast cells (3, 7-9). Signaling by RANTES is mediated by several G-protein coupled receptors (GPCRs), including CCR1, CCR3, CCR4 and CCR5.
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验26The Production of Chemokine Specific Monoclonal Antibodies: Chemokine RANTES
against the human chemokine RANTES (1 ,2 ). The general approach described here should be broadly applicable to the generation of MAbs directed against other members of this cytokine family.
Screening of Antigen-Specific Antibody-Secreting Cells
Screening of antigen-specific antibody-producing cells is a key step for obtaining antigen-specific monoclonal antibodies. In murine system, hybridoma between B-lymphocytes and myeloma cells is used to screen and produce antigen-specific
Antibody Targeting of Nanoparticles to Tumor-Specific Receptors: Immunoliposomes
Immunoliposomes generated by coupling of antibodies to the liposomal surface allow for an active tissue targeting, e.g., through binding to tumor cell-specific receptors. Instead of whole antibodies, single-chain Fv fragments (scFv
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