- 询价
- Cell Signaling Technology
- 3755
- USA
- 2025年12月24日
- W, IP, IF-IC
- Rabbit
- H,M,R
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- 详细信息
- 技术资料
- 抗体英文名：
JunB (P169) Antibody
- 抗原：
synthetic peptide corresponding to residues surrounding Pro169 of human JunB
- 应用范围：
W, IP, IF-IC
- 宿主：
Rabbit
- 适应物种：
H,M,R
- 供应商：
CST
- 级别：
详见MSDS文件
- 保质期：
详见说明书
- 库存：
大量
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IP IF-IC | H M (R) | Endogenous | 42, 43 | Rabbit |
| Protocols | |
|---|---|
| Specificity / Sensitivity | JunB (P169) Antibody detects the endogenous level of total JunB protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro169 of human JunB. Antibodies are purified by peptide affinity chromatography. Western Blotting
Western blot analysis of total cell lysates from various cell lines using JunB (P169) Antibody. IF-IC
Confocal immunofluorescent analysis of HeLa cells using JunB (P169) Antibody (green). Actin filaments have been labeled with Alexa Fluor® 555 phalloidin (red). |
| Background | JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals (1-4). While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice (5-7). JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML) (8,9).
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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