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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名:
Hexokinase I Antibody
- 抗原:
synthetic peptide corresponding to the sequence of human hexokinase I
- 应用范围:
W
- 宿主:
Rabbit
- 适应物种:
H,Mk,B
- 供应商:
CST
- 库存:
大量
- 级别:
详见MSDS文件
- 保质期:
详见说明书
- 是否单克隆:
2
- 保存条件:
-20°c
- 规格:
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格: | 产品价格: | ¥请询价 | |
|---|---|---|---|
| 规格: | 100 ul (10 western blots) | 产品价格: | ¥请询价 |
| 规格: | carrier free & custom formulation / quantity | 产品价格: | ¥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human Mk=Monkey B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | H Mk (B) | Endogenous | 102 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Hexokinase I Antibody detects endogenous levels of total hexokinase I protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human hexokinase I. Antibodies are purified by peptide affinity chromatography. |
| Background | Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验that possess an intrinsic affinity toward each other (such as antigen and antibody, or avidin and biotin). After cell lysis, endosomes are allowed to fuse in vitro in the presence of an externally added quencher that prevents complex formation between markers
only have been done and with exception of that summarized in Table 2, none has been repeated. This is clearly unsatisfactory, particularly when there is so much variation between assays. 10. The condition of incubation are poorly defined. What is the temperature? Were antibody used
that possess an intrinsic affinity toward each other (such as antigen and antibody, or avidin and biotin). After cell lysis, endosomes are allowed to fuse in vitro in the presence of an externally added quencher that prevents complex formation between markers
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