- 询价
- Cell Signaling Technology
- 4591
- USA
- 2026年05月28日
- W, IP
- Rabbit
- H
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- 文献和实验
- 技术资料
- 抗体英文名：
GATA-1 Antibody
- 抗原：
synthetic peptide corresponding to residues surrounding Pro401 of human GATA-1
- 应用范围：
W, IP
- 宿主：
Rabbit
- 库存：
大量
- 保质期：
详见说明书
- 适应物种：
H
- 供应商：
CST
- 级别：
详见MSDS文件
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IP | H | Endogenous | 43 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | GATA-1 Antibody detects endogenous levels of total GATA-1 protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro401 of human GATA-1. Antibodies are purified by peptide affinity chromatography Western Blotting
Western blot analysis of total lysates from K562 and HEL cells using GATA-1 Antibody. |
| Background | GATA proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA binding domains, which bind directly to the nucleotide sequence core element GATA (1-3). There are six vertebrate GATA proteins, designated GATA-1 to GATA-6 (3). GATA-1 is the founding member of the GATA family and is required for erythroid and megakaryocytic cell development (4,5). Mutations in GATA-1 have been linked to many human diseases, including acute megakaryoblastic leukemia in Down syndrome children (DS-AMKL), X-linked thrombocytopenia, and gray platelet syndrome (6-9).
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验人转录因子GATA结合蛋白3(GATA-3)ELISA试剂盒 说明书
人转录因子GATA 结合蛋白 3 ( GATA-3 )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 GATA-3 单抗包被于酶标板上，标准品和样品中的 GATA-3与单抗结合，加入生物素化的抗人 GATA-3 ，形成免疫复合物连接在板上，辣根过氧化物酶标记的 Streptavidin 与生物素结合，加入
标题：An animal model recapitulates human hepatic diseases associated with GATA6 mutations 期刊：PNAS（IF9.5，中科院1区） DOI：10.1073/pnas.2317801121 发表时间：2024.12.31 研究背景 Gata6是内脏器官发育的核心转录因子，在早期胚胎发育中起着关键作用。异质合子Gata6突变会引起人类心脏、胰腺、胆囊及肝脏等多种先天性疾病。由于传统的小鼠Gata6基因敲除模型
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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