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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名:
Androgen Receptor Antibody
- 抗原:
synthetic peptide corresponding to residues surrounding Ser213 of human androgen receptor
- 应用范围:
W
- 宿主:
Rabbit
- 适应物种:
H
- 库存:
大量
- 保质期:
详见说明书
- 供应商:
CST
- 级别:
详见MSDS文件
- 是否单克隆:
2
- 保存条件:
-20°c
- 规格:
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格: | 产品价格: | ¥请询价 | |
|---|---|---|---|
| 规格: | 100 ul (10 western blots) | 产品价格: | ¥请询价 |
| 规格: | carrier free & custom formulation / quantity | 产品价格: | ¥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | H | Endogenous | 110 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Androgen Receptor Antibody detects endogenous levels of total androgen receptor. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser213 of human androgen receptor. Antibodies are purified by protein A and peptide affinity chromatography. |
| Background | Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验Analysis of Androgen Receptor SUMOylation
Androgen receptor (AR) is a ligand-controlled transcription factor that is deregulated and therefore targeted in prostate cancer. In addition to androgens, AR is regulated by post-translational modifications (PTMs). SUMOylation, conjugation
In Vitro and In Vivo Silencing of the Androgen Receptor
The androgen receptor (AR) plays a pivotal role in the progression of prostate cancer from the androgen-dependent to the castration-resistant state, making it a potential target for therapy. In this chapter, we describe the preparation
Analysis of Interdomain Interactions of the Androgen Receptor
High-affinity binding of testosterone or dihydrotestosterone to the androgen receptor (AR) triggers the androgen-dependent AR NH2 - and carboxyl-terminal (N/C) interaction between the AR NH2 -terminal FXX LF motif and the activation function
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