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文献和实验This chapter describes in vitro methods for studying the Blood-Brain barrier. These methods include a cell line and isolated brain microvessels. The rat brain endothelial cell line 4 (RBE4) express many properties that are expressed by brain
The application of the suppressive subtraction hybridization (SSH) technique to blood-brain barrier (BBB) genomics has accelerated the discovery and identification of BBB-specific genes in humans and in experimental animals (
Molecular Biology of the Blood-Brain Barrier
The blood-brain barrier (BBB) is formed by the micro vasculature of the brain ( 1 ). The permeability properties, per se , of the BBB are regulated by the capillary endothelial cell ( 2
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