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CDKN1A(phospho T145) & CDKN1A Protein Phosphorylation Antibody Pair
- 参考价格： ￥7068.0
- 品 牌： abnova
- 货 号： DP0022
- 适应物种： 人
- 修 饰： phospho t145
- omim id： 116899
- 基 因 名： CDKN1A
- 基因别名： CAP20,CDKN1,CIP1,MDA-6,P21,SDI1,WAF1,p21CIP1
靶点信息
| 基因描述： | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| 基因概览： | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. [provided by RefSeq |
| 别名： | CDK-interaction protein 1,DNA synthesis inhibitor,OTTHUMP00000016298,cyclin-dependent kinase inhibitor 1A,melanoma differentiation associated protein 6,wild-type p53-activated fragment 1 |
应用与保存
| 保存条件： | Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use. |
其他
| 供应产品： | Antibody pair set content: 1. Phospho-CDKN1A T145 rabbit polyclonal antibody (20 ul) With 0.09% sodium azide. 2. CDKN1A mouse monoclonal antibody (40 ug) In 1x PBS, pH 7.2 *Reagents are sufficient for at least 30-50 assays using recommended protocols. |
| 描述： | This protein phosphorylation antibody pair set comes with two antibodies, one against the CDKN1A protein, and the other against the specific T145 phosphorylated site of CDKN1A for use in in situ Proximity Ligation Assay . See Publication Reference below . |
| 规格： | 1 Set | 价格： | ￥7068 |
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