alpha+beta Synuclein兔单抗

2022-06-28 15:12点击次数:96

关键词:alpha+betaSynuclein兔单抗
来源用途交叉反应性分子量
RabbitWB, IF, IHC, ICC, FCH, M, R18.0kDa

WB, Western blot; IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry; ICC, Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent Assay; ChIP, Chromatin Immunoprecipitation Assay.
H, Human; M, Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr, Horse; Mk, Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, Zebrafish; All, all species expected.
配套提供了Western一抗稀释液,可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整):

WBIPIFIHCICCFCELISAChIP
1:1,000-1:2,000-1:50-1:2001:50-1:2001:50-1:2001:50-1:100--

抗体详细信息如下:

About this Antibody
Namealpha+beta Synuclein Rabbit Monoclonal Antibody
CategoryRabbit Monoclonal Antibody (RabMAb); Primary antibody
IsotypeIgG
PurificationAffinity purification
About the Immunogen
ImmunogenRecombinant protein
Gene ID6622/6620(Human); 20617/104069(Mouse); 29219/ 113893(Rat)
SwissProtP37840/Q16143(Human); O55042/Q91ZZ3(Mouse); P37377/Q63754(Rat)
SynonymsNACP; PARK1; PARK4; PD1; SNCA; SNCB
CategoryNeuronal Signaling
BackgroundThe synucleins, including α-synuclein (also designated NACP for nonamyloid component precursor), β-synuclein (also designated PNP 14 for phospho-neuroprotein 14) and γ-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. Synucleins are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-Synuclein, identified as a component of Alzheimer's disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of α-synuclein and β-synuclein may be important during hematopoetic cell differentiation. A mutant form of α-synuclein is found in patients with early onset Parkinson's disease. γ-Synuclein is associated with axonal pathology in Parkinson's disease.