Yeast Artificial Chromosome Recombinants in a Global Strategy for Chromosome Mapping: Amplification of Internal and Terminal Fragments by PCR, and Gen
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The large cloning capacity of Yeast Artificial Chromosomes (YACs) (1 ) makes them a powerful reagent for long-range mapping and cloning toward contiguous chromosomal maps. Full value is to be attained through an integrated, global strategy (Fig. 1 ), including both
