CarbonCarbon Bond-Forming Enzymes for the Synthesis of Non-natural Amino Acids
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An enzymatic methodology for the preparation of β-hydroxy-α-amino acid derivatives is described. The method consists of the stereoselective aldol addition reaction of glycine to N -Cbz-amino aldehydes furnishing 3-hydroxy-2,4-diaminobutyric derivatives.
![ethyl 2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate，4815-29-6，阿拉丁](https://img1.dxycdn.com/p/s14/2024/0619/436/6771562959809633081.jpg!wh200)
