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        2-O,4-C-Methyleneoxymethylene Bridged Nucleic Acids (2,4-BNACOC)

        互联网

        2272
        The synthesis of 2′-O ,4′-C -methyleneoxymethylene bridged nucleoside (2′,4′-BNACOC ) phosphoramidites and oligonucleotides containing 2′,4′-BNACOC are described. 2′,4′-BNACOC phosphoramidites bearing natural nucleobases, such as thymine, cytosine, 5-methylcytosine, adenine, and guanine were synthesized. Moreover, fully or partially 2′,4′-BNACOC -modified oligonucleotides can be prepared by using a standard protocol except for a prolonged coupling time on an automated DNA synthesizer.
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        相关问答

        问

        进行正态w检验（o=0.05）？

        315 围观
        2023-11-20

        问

        O/E ratio 这个指标怎么计算呢？

        4 回答 2263 围观
        2023-01-07

        问

        同一个批号的质控，同一天用，有的批次质控测不出o基因，有的又能测出o基因，请问是质控问题还是仪器问题？

        5 回答 599 围观
        2022-06-14

        相关方法

        油红 O 染色

        测定伤寒杆菌“O”抗体

        中性脂肪油红 O 显示技术

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