Immobilization of Cells With Transition Metal

The use of transition metal-based supports for cell immobilization has proved its feasibility in some fermentative or bioconversion processes with potential for commercial-scale application in the food industry. It was therefore logical to evaluate the validity of this immobilization method within the development of other relevant bioprocesses, such as steroid bioconversions. Among the transition metal-based supports, titanium-based supports are by far the most widely used for whole cell immobilization. In order to illustrate this concept, some practical approaches for the immobilization of yeast and bacterial cells onto titanium-based supports, aiming for the production of biocatalysts with application in bioconversion processes, are presented in this work