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        Selection of Transfected Cells and Coamplification of Transfected Genes

        互联网

        446
        There are many applications for gene transfer and gene expression technology in mammalian somatic cell biology. Whether for functional analysis of a newly cloned gene or for purifying large amounts of a protein for its subsequent biochemical characterization, it is often important to overexpress foreign genes in the “native” environment of a mammalian cell. Furthermore, rapidly developing gene therapy technology relies on the ability to express foreign sequences at significant levels in a stable, long-term fashion.
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