Immunochemical Method for Ochratoxin A
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Ochratoxin A (7-L-β-phenylalanylcarbonyl-5-chloro-8-hydroxy-3,4-dihydro-3-R-methylisocoumarin, Fig. 1
) was first isolated in 1965 from A. ochraceus
(1
). Meanwhile several Aspergillus
and Penicillium
species are known to produce ochratoxin A. The toxin frequently occurs as a contaminant in plant products worldwide, predominantly
during storage. Numerous papers have described its occurrence in, for example, cereals, beans, coffee, grapes, beer, and red
wine (2
,3
). In particular for Penicillium
spp., cocontamination with ochratoxin A and other Penicillium
toxins, such as citrinin, is quite common (4
).
Fig. 1.
Structural formula for ochratoxin A.
