Microsatellite Analysis in Plasmodium falciparum
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Microsatellites (MS) are simple sequence repeats (SSRs) such as (CA)n , (TAA)n , or (TA)n that have been found in all eukaryotes studied (1 -3 ). The number of repeated nucleotides per unit is generally limited to between 1 and 5, in contrast to the longer repeats characteristic of minisatellites. Whereas (CA)n and (GT)n are the most abundant repeats in mammals, (TA)n and (TAA)n are the most common SSRs in plants (4 ). Similar to many plants, the genome of the human malaria parasite, Plasmodium falciparum , is rich in A-T SSRs, particularly (TA)n and (TAA)n (5 ).
