Double-Isotope Dansyl Microassay for Cerebral Amino Acids
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1-Dimethylammo-naphthalene-5-sulfonyl chloride (dansyl chloride, Fig. 1
) was originally used by Weber in 1952 for the formation of fluorescent conjugates of albumin. Dansyl chloride reacts with
primary and secondary amino groups and with phenols.
Fig 1
Structure of dansyl chloride
![N-[2-[4-[[6-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]-2-azaspiro[3.3]heptan-2-yl]methyl]cyclohexyl]-5-(2-hydroxypropan-2-yl)-1,3-benzothiazol-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide，Moligand™，阿拉丁](https://img1.dxycdn.com/p/s14/2024/0619/785/8670042233826733081.jpg!wh200)
