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        Internet Basics

        互联网

        712
        • Abstract
        • Table of Contents
        • Figures
        • Literature Cited

        Abstract

        With the explosion of sequence and structural information available to researchers, the field of bioinformatics is playing an increasingly large role in the study of fundamental biomedical problems. The challenge facing computational biologists will be to aid in gene discovery and in the design of molecular modeling, site?directed mutagenesis, and experiments of other types that can potentially reveal previously unknown relationships with respect to the structure and function of genes and proteins. This challenge becomes particularly daunting in light of the vast amount of data that has been produced by the Human Genome Project and other systematic sequencing efforts to date. This unit begins with a review of the Internet and its terminology, also discussing major classes of Internet protocols, without becoming overly engaged in the engineering minutiae underlying these protocols. Matters of connectivity, ranging from simple modem connections to digital subscriber lines (DSL) are also discussed. Finally, one of the most common problems that has arisen with the proliferation of Web pages throughout the world is addressed??i.e., finding useful information on the World Wide Web.

        GO TO THE FULL PROTOCOL:
        PDF or HTML at Wiley Online Library

        Table of Contents

        • Internet Basics
        • Connecting to the Internet
        • Electronic Mail
        • File Transfer Protocol
        • The World Wide Web
        • Literature Cited
        • Figures
        • Tables
        GO TO THE FULL PROTOCOL:
        PDF or HTML at Wiley Online Library

        Materials

        GO TO THE FULL PROTOCOL:
        PDF or HTML at Wiley Online Library

        Figures

        • Figure 2.4.1 Performance of various types of Internet connections, by maximum throughput. The numbers indicated in the graph refer to peak performance; often the actual performance of any given method may be on the order of one‐half slower, depending on configurations and system conditions.
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        • Figure 2.4.2 Anatomy of an e‐mail message, with relevant components indicated. This message is an automated reply to a request for help file for the PredictProtein E‐mail server.
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        • Figure 2.4.3 Using NewsWatcher to read postings to newsgroups. The list of newsgroups that the user has subscribed to is shown in the Subscribed List window (left). The list of new postings for the highlighted newsgroup ( bionet.genome.arabidopsis ) is shown in the center window. The window in the foreground shows the contents of the posting selected from the center window.
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        • Figure 2.4.4 Using UNIX FTP to download a file. An anonymous FTP session is established with the molecular biology FTP server at the University of Indiana to download the ClustalW alignment program. The user inputs are shown in boldface.
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        • Figure 2.4.5 Using Fetch to download a file. An anonymous FTP session is established with the molecular biology FTP server at the University of Indiana (top) to download the ClustalW alignment program (bottom). Notice the difference between this GUI‐based program and the UNIX equivalent illustrated in Figure .
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        Videos

        Literature Cited

        Literature Cited
        Froehlich, F. and Kent, A. 1991. ARPANET, the Defense Data Network, and Internet. In Encyclopedia of Communications. Marcel Dekker, New York.
        Kennedy, A.J. 1999. The Internet: Rough Guide 2000. Rough Guides, London.
        Krol, E. and Klopfenstein, B.C. 1996. The Whole Internet User's Guide and Catalog. O'Reilly and Associates,, Sebastopol Calif.
        Lawrence, S. and Giles, C.L. 1998. Searching the World Wide Web. Science 280:98‐100.
        Rankin, B. 1996. Dr. Bob's Painless Guide to the Internet and Amazing Things You Can Do with E‐mail. No Starch Press, San Francisco.
        Quarterman, J. 1990. The Matrix: Computer Networks and Conferencing Systems Worldwide. Digital Press, Bedford, Mass.
        GO TO THE FULL PROTOCOL:
        PDF or HTML at Wiley Online Library

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