In Vitro Regulation of Colony Stimulating Factor-Mediated Hematopoiesis in Healthy Individuals and Patients with Different Types of Myeloproliferative
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Human hematopoiesis is initiated by hematopoietic stem cells, the most undifferentiated cell type in the bone marrow. Although hematopoietic stem cells are not yet fully identified, their function is well characterized. They are able to replicate by cell division producing daughter cells with identical properties (self-renewal), differentiate into all myeloid and lymphoid cell lineages, and have a long life-span.
