Bioreactor Culture Techniques for Cartilage-Tissue Engineering

Tissue engineering is a major focus of biotechnological research today, with the expectation that this type of technique will ultimately transform medical practice (1 ). The most ambitious tissue-engineering schemes assume that specific tissues and organs will be restored, in a multistage fabrication procedure. For example, cells derived from the patient may be processed to increase the total number available, seeded into a suitable three-dimensional (3D) resorbable scaffold and further processed in vitro to induce the elaboration of neo-tissue prior to implantation (2 ).