Properties of Retinoids: Structure, Handling, and Preparation
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Retinolds have been defined as a class of compounds consisting of four isoprenoid units (H
2
C=C(CH
3
)-CH=CH
2
) joined in a head-to-tail manner. The retinoid molecule can be divided into three parts: a trimethylated cyclohexene ring, a conjugated tetraene side chain, and a polar carbon-oxygen functional group. Retinol (I), retinaldehyde (II), and retinoic acid (III), as well as their derivatives whose structures are shown in
Structure 1
(
1
), are included by this definition.
