【资源】2个miRNA的数据库
丁香园论坛
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浏览核酸研究2006年数据库专刊的时候，发现了两个miRNA的序列数据库。
miRNAmap:
[color\blue]http://nar.oxfordjournals.org/content/vol34/suppl_1/index.dtl
what is miRNmap
We establish genomic maps for microRNA precursors and their mapping to targets in vertebrate genomes, namely miRNAMap. In this system we collect published miRNAs from the microRNA registry (Griffiths-Jones S. et al, 2004) and predict putative miRNA precursors by RNAz which is based on genome-wide mapping of conserved RNA secondary structures from UCSC clustering (Washietl 2005). We also predict the mature miRNAs by an algorithm which is based on MDD (maximal dependence decomposition), all of the putative and known mature miRNAs have been detected their targets by miRanda (Enright et al, 2003) and RNAhybrid (Rehmsmeier et al,2004) results.
下面是这个数据库的教程：
[iframe]http://mirnamap.mbc.nctu.edu.tw/html/tutorial.html[/iframe]
miRbase
http://microrna.sanger.ac.uk/sequences/index.shtml
miRBase (http://microrna.sanger.ac.uk/) is the new home of microRNA data on the web, providing data previously accessible from the miRNA Registry. Old miRNA Registry addresses should redirect you to this page.
~undefined The miRBase Sequence Database is a searchable database of published miRNA sequences and annotation. The data were previously provided by the miRNA Registry.
~undefined The miRBase Registry continues to provide gene hunters with unique names for novel miRNA genes prior to publication of results.
~undefined The miRBase Targets database is a new resource of predicted miRNA targets in animals.
Each entry in the miRBase Sequence database represents a predicted hairpin portion of a miRNA transcript (termed mir in the database), with information on the location and sequence of the mature miRNA sequence (termed miR). Both hairpin and mature sequences are available for searching using BLAST and SSEARCH, and entries can also be retrieved by name, keyword, references and annotation. All sequence and annotation data are also available for download.
核酸研究关于这两个数据库的介绍文章：
miRNAmap
http://nar.oxfordjournals.org/cgi/reprint/34/suppl_1/D135
miRbase:
http://nar.oxfordjournals.org/cgi/content/full/34/suppl_1/D140
miRNAmap:
[color\blue]http://nar.oxfordjournals.org/content/vol34/suppl_1/index.dtl
what is miRNmap
We establish genomic maps for microRNA precursors and their mapping to targets in vertebrate genomes, namely miRNAMap. In this system we collect published miRNAs from the microRNA registry (Griffiths-Jones S. et al, 2004) and predict putative miRNA precursors by RNAz which is based on genome-wide mapping of conserved RNA secondary structures from UCSC clustering (Washietl 2005). We also predict the mature miRNAs by an algorithm which is based on MDD (maximal dependence decomposition), all of the putative and known mature miRNAs have been detected their targets by miRanda (Enright et al, 2003) and RNAhybrid (Rehmsmeier et al,2004) results.
下面是这个数据库的教程：
[iframe]http://mirnamap.mbc.nctu.edu.tw/html/tutorial.html[/iframe]
miRbase
http://microrna.sanger.ac.uk/sequences/index.shtml
miRBase (http://microrna.sanger.ac.uk/) is the new home of microRNA data on the web, providing data previously accessible from the miRNA Registry. Old miRNA Registry addresses should redirect you to this page.
~undefined The miRBase Sequence Database is a searchable database of published miRNA sequences and annotation. The data were previously provided by the miRNA Registry.
~undefined The miRBase Registry continues to provide gene hunters with unique names for novel miRNA genes prior to publication of results.
~undefined The miRBase Targets database is a new resource of predicted miRNA targets in animals.
Each entry in the miRBase Sequence database represents a predicted hairpin portion of a miRNA transcript (termed mir in the database), with information on the location and sequence of the mature miRNA sequence (termed miR). Both hairpin and mature sequences are available for searching using BLAST and SSEARCH, and entries can also be retrieved by name, keyword, references and annotation. All sequence and annotation data are also available for download.
核酸研究关于这两个数据库的介绍文章：
miRNAmap
http://nar.oxfordjournals.org/cgi/reprint/34/suppl_1/D135
miRbase:
http://nar.oxfordjournals.org/cgi/content/full/34/suppl_1/D140
